Protease-activated receptor-4: a novel mechanism of inflammatory pain modulation
โ Scribed by S Asfaha; N Cenac; S Houle; C Altier; M D Papez; C Nguyen; M Steinhoff; K Chapman; G W Zamponi; N Vergnolle
- Book ID
- 110009363
- Publisher
- Nature Publishing Group
- Year
- 2007
- Tongue
- English
- Weight
- 184 KB
- Volume
- 150
- Category
- Article
- ISSN
- 0007-1188
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๐ SIMILAR VOLUMES
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
In the present study, we explored the molecular mechanisms by which bacterial endotoxin (LPS) mediates the down-regulation of CCR2 receptors on human monocytes. We found that LPS induced a marked reduction in CCR2 cell surface protein levels which was blocked by pretreatment with the tyrosine kinase