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Modulation of visceral pain and inflammation by protease-activated receptors

✍ Scribed by Nathalie Vergnolle

Book ID: 110008274
Publisher: Nature Publishing Group
Year: 2004
Tongue: English
Weight: 369 KB
Volume: 141
Category: Article
ISSN: 0007-1188
DOI: 10.1038/sj.bjp.0705750

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## Abstract ## Objective To investigate the role of proteinase‐activated receptor 4 (PAR‐4) in mediating joint inflammation and pain in mice. ## Methods Knee joint blood flow, edema, and pain sensitivity (as induced by thermal and mechanical stimuli) were assessed in C57BL/6 mice following intra