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Protease-activated receptor 2 signaling in inflammation

✍ Scribed by Andrea S. Rothmeier; Wolfram Ruf

Publisher
Springer-Verlag
Year
2011
Tongue
English
Weight
457 KB
Volume
34
Category
Article
ISSN
1863-2297

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## Abstract Protease‐activated receptors (PARs) are a unique family of G‐protein‐coupled receptors (GPCRs) that are irreversibly activated following proteolytic cleavage of their extracellular N‐terminus. PARs play critical functions in hemostasis, thrombosis, inflammation, embryonic development, a