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Protease-Activated Receptor-2 Reduces Cyclohexamide-Induced Apoptosis in K562 Myeloid Leukemia Cells

✍ Scribed by Sriwai, Wimolpak ;Murthy, Karnam S. ;Srisawang, Prassanee ;Maladad, Kanteera


Book ID
122146852
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
44 KB
Volume
140
Category
Article
ISSN
0016-5085

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## Abstract Cepharanthine (CEP) is a known membrane stabilizer that has been widely used in Japan for the treatment of several disorders such as anticancer therapy‐provoked leukopenia. We here report that apoptosis was induced by low concentrations (1–5 ΞΌM) of CEP in a human leukemia T cell line, J