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Protease activated receptor 2 and the cardiovascular system

✍ Scribed by Carla Cicala

Book ID: 110006041
Publisher: Nature Publishing Group
Year: 2002
Tongue: English
Weight: 211 KB
Volume: 135
Category: Article
ISSN: 0007-1188
DOI: 10.1038/sj.bjp.0704438

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## Abstract Protease‐activated receptor 2 (PAR~2~) is a G protein‐coupled cell surface receptor for trypsin‐like enzymes. Proteolytic cleavage at a specific site in the extracellular __N__‐terminus exposes a receptor‐activating sequence, the ‘tethered ligand’, which binds intramolecularly to initia