Prostatic intraepithelial neoplasia (PIN) represents the putative precancerous end of the morphologic continuum of cellular proliferations within prostatic ducts, ductules and acini. Two gradesof PIN are identified (low grade and high grade), and high grade PIN is considered to be a precursorto inva
Prostatic Intraepithelial Neoplasia (PIN): Importance and Clinical Management
β Scribed by S. Joniau; L. Goeman; J. Pennings; H. Van Poppel
- Book ID
- 113608921
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 229 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0302-2838
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Quantitative analyses (QAs) of prostatic intraepithelial neoplasia (PIN) helped to objectively define some traditional features of the lesion because, first, changes in value are represented by numbers and not by subjective evaluation of morphologic clues. QAs have also helped to identify subtle abn
## Background: Prostatic intraepithelial neoplasia (pin) is the most likely precursor of prostatic adenocarcinoma. however, the ultrastructural features of pin have not been defined in properly fixed tissues. ## Methods: In this study, we examined a total of 84 acini from 11 cases of high-grade p