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Prostate-specific antigen, its molecular forms, and other kallikrein markers for detection of prostate cancer

✍ Scribed by Carsten Stephan; Klaus Jung; Eleftherios P Diamandis; Harry G Rittenhouse; Michael Lein; Stefan A Loening


Book ID
117264059
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
130 KB
Volume
59
Category
Article
ISSN
0090-4295

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## BACKGROUND. Human glandular kallikrein (hK2), the prostate specific antigen (PSA) close homologue, possesses approximately 80% structure identity with PSA. The identification of PSA was an important step in the detection of prostate carcinoma (PCa). Thus, hK2 measurement in the serum has the po

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## Objectives: To examine the diagnostic value of prostate-specific antigen (psa) subfractions in the serum of female breast cancer patients. ## Design and methods: Psa subfractions (free psa, f-psa; psa bound to alpha 1-antichymotrypsin, psa-act) were determined in the serum of patients with bre