## Abstract Prostate cancer (PCa) preferentially metastasizes to bone resulting in osteoblastic lesions with underlying osteolytic activities. The mechanisms through which PCa cells promote osteolytic activities and subsequent osteoblastic bone formation remain poorly understood. Parathyroid hormon
Prostate cancer cells modulate osteoblast mineralisation and osteoclast differentiation through Id-1
β Scribed by Yuen, H-F; Chiu, Y-T; Chan, K-K; Chan, Y-P; Chua, C-W; McCrudden, C M; Tang, K-H; El-Tanani, M; Wong, Y-C; Wang, X
- Book ID
- 110000287
- Publisher
- Nature Publishing Group
- Year
- 2009
- Tongue
- English
- Weight
- 678 KB
- Volume
- 102
- Category
- Article
- ISSN
- 0007-0920
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## Abstract Resistance to anticancer drugs is the major problem in the treatment of many advanced cancers, including androgenβindependent prostate cancer. Recently, increased expression of Idβ1, a basic helixβloopβhelix protein, is reported in several types of advanced cancer. It is suggested that