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Prostaglandin Levels in Human Colorectal Mucosa (Effects of Sulindac in Patients with Familial Adenomatous Polyposis)

โœ Scribed by Raymond N. Dubois; Linda M. Hylind; C. Rahj Robinson; Walter C. Hubbard; Stanley R. Hamilton; Vincent W. Yang; Francis M. Giardiello; Ernst W. Spannhake


Book ID
110379090
Publisher
Springer US
Year
1998
Tongue
English
Weight
231 KB
Volume
43
Category
Article
ISSN
0163-2116

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## BACKGROUND. Oral sulindac is known to reduce polyps in patients with familial adenomatous polyposis (FAP). The authors speculated that rectal administration of indomethacin would he effective therapy for adenomas in the rectal remnant of FAP. METHODS. Eight patients with FAP who had been treate