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Prostaglandin E2 stimulates rat and human colonic mucin exocytosis via the EP4 receptor

โœ Scribed by Adam Belley; Kris Chadee

Book ID
118521882
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
284 KB
Volume
117
Category
Article
ISSN
0016-5085

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## Abstract Elevated levels of prostaglandins such as PGE~2~ in inflamed gingiva play a significant role in the tissue destruction caused by periodontitis, partly by targeting local fibroblasts. Only very few studies have shown that PGE~2~ inhibits the proliferation of a gingival fibroblast (GF) ce