𝔖 Bobbio Scriptorium
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Prostaglandin E2 stimulates Fas ligand expression via the EP1 receptor in colon cancer cells

✍ Scribed by O'Callaghan, G; Kelly, J; Shanahan, F; Houston, A


Book ID
109999584
Publisher
Nature Publishing Group
Year
2008
Tongue
English
Weight
430 KB
Volume
99
Category
Article
ISSN
0007-0920

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We previously reported that cycloogenase (COX)-2-generated prostaglandin E2 (PGE2) had anti-apoptotic effects in UVB-exposed mouse skin that involved EP2-mediated signaling (Chun et al., Cancer Res. 2007; 67: 2015). Because survivin is a regulator of cell survival, the possible involvement of COX-2