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Prostaglandin E2 increases bone strength in intact rats and in ovariectomized rats with established osteopenia

โœ Scribed by H.Z Ke; V.W Shen; H Qi; D.T Crawford; D.D Wu; X.G Liang; K.L Chidsey-Frink; C.M Pirie; H.A Simmons; D.D Thompson


Book ID
117808645
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
300 KB
Volume
23
Category
Article
ISSN
8756-3282

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To determine whether the uterus plays any role in mediating the ability of estrogen to conserve bone in the rat, eight groups of animals (n = 8) with their skeletons labeled with 45Ca were studied. Rats were ovariectomized (OVX), hysterectomized (Hyst), or given sham operations (Sham) and then pair-