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Prostaglandin chemistry—V : Synthesis of new prostaglandin synthons; 4(R)-(+)- and 4(S)-(−)-t-butyldimethylsiloxycyclopent-2-en-1-one

✍ Scribed by T. Tanaka; S. Kurozumi; T. Toru; S. Miura; M. Kobayashi; S. Ishimoto


Book ID
103399315
Publisher
Elsevier Science
Year
1976
Tongue
French
Weight
952 KB
Volume
32
Category
Article
ISSN
0040-4020

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Electroorganic synthesis, 56. Synthesis
✍ Weiguny, Jens ;Schäfer, Hans J. 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 964 KB

## Abstract The key intermediate of a novel synthesis of prostaglandin precursors, (1′__R__,4′__S__,3__R__/__S__)‐3‐(__cis__‐4‐acetoxycyclopent‐2‐enyl oxy)‐3‐ethoxypropionic acid (3), is prepared by two different synthetic sequences: In a first strategy transacetalization of ethyl 3,3‐diethoxypropi