epatocyte transplantation has the potential to H play an important role in specific hepatic disease states such as inborn errors of metabolism and acute hepatic failure. Although considerable progress has been made in the development of hepatocyte transplantation as a viable clinical entity, it has
Prospects for hepatocyte transplantation
β Scribed by Ginny L. Bumgardner; Carlos Fasola; David E. R. Sutherland
- Publisher
- John Wiley and Sons
- Year
- 1988
- Tongue
- English
- Weight
- 552 KB
- Volume
- 8
- Category
- Article
- ISSN
- 0270-9139
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Liver cell transplantation may provide a means to replace lost or deficient liver tissue, but devices capable of delivering hepatocytes to a desirable anatomic location and guiding the development of a new tissue from these cells and the host tissue are needed. We have investigated whether sponges f
## Key Points 1. Our increasing understanding of signaling pathways and cellular interactions in transplant immunobiology and the availability of novel immunosuppressive agents have facilitated targeted strategies. 2. The driving forces behind the development of new immunosuppressive regimens are t
Hepatocyte transplantation (HT) is an attractive therapeutic modality for liver disease as an alternative for liver organ transplantation. Primary fresh hepatocytes (FHs) are the exclusive cell source that has been used for clinical HT. However, the use of FHs is limited due to a shortage of donor c