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Prospects for adoptive T cell therapy

✍ Scribed by Cassian Yee; Stanley R Riddell; Philip D Greenberg

Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
796 KB
Volume
9
Category
Article
ISSN
0952-7915

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✦ Synopsis

Since the establishment of methods to isolate genes encoding cytotoxic T lymphocyte defined tumor antigens, several antigens have been identified and characterized for suitability as target antigens for immunotherapy. The development of innovative strategies to generate T cells targeting these antigens and lessons learned from clinical trials of adoptive immunotherapy of viral diseases should facilitate the design of clinical trials for specific adoptive immunotherapy of cancer.

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