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Prospects for intravascular gene therapy

✍ Scribed by Roy C. Smith; Kenneth Walsh


Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
38 KB
Volume
12
Category
Article
ISSN
0733-2459

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✦ Synopsis


The goal of this review is to provide an overview of gene delivery systems and candidate genes currently being evaluated for genetic strategies in vascular gene therapy. We will discuss treatment strategies that have been shown by in vivo model systems to be efficacious in promoting neovascularization of ischemic tissue or limiting postinterventional restenosis by inhibiting smooth muscle cell proliferation and/or encouraging re-endothelialization. J. Clin. Apheresis 12:140-145, 1997.


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