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Proportion of lung cancers due to occupational exposure

✍ Scribed by Ugo Pastorino; 2Franco Berrino; Antonio Gervasio; Vittorio Pesenti; Elio Riboli; Paolo Crosignan

Publisher
John Wiley and Sons
Year
1984
Tongue
French
Weight
726 KB
Volume
33
Category
Article
ISSN
0020-7136

No coin nor oath required. For personal study only.

✦ Synopsis

The proportions of male lung cancers due to occupational exposure and, respectively, to cigarette smoking in a highly industrialized area of Northern Italy were esti- mated in a population-based case-control study in 1976-9.

Two hundred and four out of the 2 I I lung cancer cases and 351 controls sampled from the source population were questioned about their occupational and smoking histories. On the basis of the occupational history each subject was classified as probably exposed (+), possibly exposed (I), or unexposed (-) to one or more of the chemicals known to be carcinogenic for the human lung, namely asbestos, po!ycyclic aromatic hydrocarbons, arsenic, nickel and chromium compounds, BCME, CMME and vinyl chloride. Upon stratification by cigarette smoking, contrasting the occupationally exposed subjects, whether certainly or uncertainly defined, with the unexposed ones, the RR for lung cancer was 2. I and the occupational etiologic fraction was 0.33 (95 % confidence interval 0.19-0.47). The 4~~ whom reprint requests should be sent.

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