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Occupational exposure and lung cancer risk

✍ Scribed by Gunnar Kvåle; Erik Bjelke; Ivar Heuch

Publisher
John Wiley and Sons
Year
1986
Tongue
French
Weight
839 KB
Volume
37
Category
Article
ISSN
0020-7136

No coin nor oath required. For personal study only.

✦ Synopsis

The importance of occupation held longest as a risk factor for lung cancer was examined in a prospective study in Norway of 11,995 men, among whom 125 cases occurred in a follow-up from 1966 through 1978.

Based on information about occupation held longest, the respondents were classified into 3 groups according to suspected exposure to respiratory carcinogens at the workplace. After stratification for age, place of residence and cigarette smoking, we found a highly significant relative risk of 2.6 for those judged to have experienced definite exposure versus the group with no workplace exposure. The apparent risk-enhancing effect of occupational exposure was observed for all histologic subtypes. Stratification including a socioeconomic factor score led to a moderate reduction in the relative risk estimate. High risk estimates still obtained, however, for a limited number of occupations, the highest for workers in the mining and quarrying industries. Although the interpretation of the observed effect associated with a crude index of occupational exposure may be difficult, our results suggest that between 13 and 2746 of the lung cancer cases observed among Norwegian men in the relevant time period can be attributed to harmful work-place exposure.

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