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Propolis induces cell cycle arrest and apoptosis in human leukemic U937 cells through Bcl-2/Bax regulation

โœ Scribed by Muneo Motomura; Kyung Min Kwon; Seok-Jong Suh; Young-Choon Lee; Yeon-Kye Kim; In-Seon Lee; Myung-Sunny Kim; Dae Young Kwon; Ikukatsu Suzuki; Cheorl-Ho Kim


Book ID
116454709
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
535 KB
Volume
26
Category
Article
ISSN
1382-6689

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## Abstract 2โ€Methoxyestradiol (2ME) is an endogenous metabolite with estrogen receptorโ€independent antiโ€tumor activity. The current study seeks to determine the mechanism of antiโ€tumor activity of 2ME on human chondrosarcoma. 2ME caused a timeโ€ and doseโ€dependent cytotoxity in chondrosarcoma cells