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Propionibacterium acnes sensitizes the liver for toll-like receptor 4, not for Tlr2 mediated injury involving up-regulation of the Tlr4/Md-2 receptor complex

โœ Scribed by Romics, Laszlo; Kodys, Karen; Li, Weibo; Dolganiuc, Angela; Szabo, Gyongyi


Book ID
123493163
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
249 KB
Volume
124
Category
Article
ISSN
0016-5085

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Selective priming to Toll-like receptor
โœ Laszlo Romics Jr.; Angela Dolganiuc; Karen Kodys; Yvonne Drechsler; Shilpa Oak; ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 920 KB

Lipopolysaccharide (LPS) triggers cytokine production through Toll-like receptor 4 (TLR4), which shares downstream signaling pathways with TLR2. We investigated the roles of TLR2 and TLR4 in Propionibacterium acnes (P. acnes)-primed, LPS-induced liver damage using selective TLR ligands. Stock LPS in

Toll-like receptor 2 (TLR2) and TLR4 are