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Selective Roles for Toll-Like Receptor (TLR)2 and TLR4 in the Regulation of Neutrophil Activation and Life Span

✍ Scribed by Sabroe, I.; Prince, L. R.; Jones, E. C.; Horsburgh, M. J.; Foster, S. J.; Vogel, S. N.; Dower, S. K.; Whyte, M. K. B.


Book ID
121863661
Publisher
American Association of Immunologists
Year
2003
Tongue
English
Weight
562 KB
Volume
170
Category
Article
ISSN
0022-1767

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## Abstract Severe injury deranges immune function and increases the risk of sepsis and multiple organ failure. Kupffer cells play a major role in mediating posttraumatic immune responses, in part via different Toll‐like receptors (TLR). Although mitogen‐activated protein kinases (MAPK) are key ele