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Properties of tryptophan hydroxylase from human carcinoid tumor

✍ Scribed by Syun Hosoda; Wataru Nakamura; Kiyoshi Takatsuki


Book ID
115734707
Publisher
Elsevier Science
Year
1977
Weight
493 KB
Volume
482
Category
Article
ISSN
0005-2744

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Tryptophan hydroxylase 2 (TPH2) catalyzes the rate-limiting step in serotonin biosynthesis in the nervous system. Several variants of human TPH2 have been reported to be associated with a spectrum of neuropsychiatric disorders such as unipolar major depression, bipolar disorder, suicidality, and att