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Properties of SV40 rescued from actinomycin D-sensitive and actinomyein D-resistant transformed hamster cells

โœ Scribed by H. G. Suarez; R. Cassingena; S. Estrade; R. Wicker; Ch. Lavialle; P. Lazar


Publisher
Springer Vienna
Year
1974
Tongue
English
Weight
734 KB
Volume
46
Category
Article
ISSN
1432-8798

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## Abstract The biological properties of a hamster cell line Cl 2 TSVโ€5/R derived from an SV40 tumour and made resistant to Actinomycin D (2 ฮผg/ml) were investigated, in particular: tumorigenicity in vitro growth on plastic or in soft agar, agar, persistence of SV40 specific neoantigens (T and TSTA

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Plasma membrane proteins and glycoproteins have been isolated from Chinese hamster cells of the spontaneously transformed DC-3F parental cell line and the DC-3F/AD X line with a high level of acquired resistance to actinomycin D. Plasma membrane preparations from both cell lines band at 1.16 g/ml af