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Properties of cytochrome P450 isoenzymes and their substrates part 2: properties of cytochrome P450 substrates

✍ Scribed by Dennis A. Smith; Mark J. Ackland; Barry C. Jones

Book ID
114385501
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
959 KB
Volume
2
Category
Article
ISSN
1359-6446

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## Abstract Cytochrome P450 (P450) enzymes catalyze a variety of oxidation and some reduction reactions, collectively involving thousands of substrates. A general chemical mechanism can be used to rationalize most of the oxidations and involves a perfenyl intermediate (FeO^3+^) and odd‐electron che