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Properties of a 9-(2-phosphonylmethoxyethyl)adenine (PMEA)-resistant herpes simplex virus type 1 virus mutant

✍ Scribed by Vladimír Vonka; Emma Anisimová; Jaroslav Černý; Antonín Holy; Ivan Rosenberg; Ivan Votruba

Book ID
118392209
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
554 KB
Volume
14
Category
Article
ISSN
0166-3542

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## Abstract A small‐plaque mutant (No. 69) of herpes simplex virus type 2 (HSV‐2) strain 333 has been previously isolated and characterized in this laboratory. This mutant was shown to produce a high ratio of noninfectious to infectious particles when grown at the nonpermissive temperature in hamst