## Abstract Sera and synovial fluids from 88 patients with rheumatoid arthritis were examined for circulating immune complexes by three assays: monoclonal rheumatoid factor radioimmunoassay, Clq binding assay, and Raji cell radioassay. Paired samples were available for 82 patients. Immune complexes
Properties and reactivity of immune complexes in rheumatoid synovial fluid
β Scribed by E. Mochan; T. J. Passon
- Publisher
- Springer
- Year
- 1986
- Tongue
- English
- Weight
- 674 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0172-8172
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Synovial fluid (SF) from patients with rheumatoid arthritis (RA) enhanced superoxide generation by neutrophils isolated from RA SF, in contrast to SF from patients with osteoarthritis. These superoxide generation-enhancing substances may be intermediate-sized immune complexes and a complement C5-der
## Abstract Fiftyβsix sera and 33 synovial fluids from rheumatoid arthritis patients were studied to evaluate their capacity to solubilize immune complexes. A decreased function was found in 65% of rheumatoid synovial fluids when compared with 13 osteoarthritis synovial fluids. The decrease of immu