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Propargylamine Synthesis by Copper-Catalyzed Oxidative Coupling of Alkynes and Tertiary Amine N -Oxides

✍ Scribed by Xu, Zhanwei; Yu, Xiaoqiang; Feng, Xiujuan; Bao, Ming


Book ID
120012647
Publisher
American Chemical Society
Year
2011
Tongue
English
Weight
799 KB
Volume
76
Category
Article
ISSN
0022-3263

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An efficient synthesis of propargylamine
✍ M. Lakshmi Kantam; Soumi Laha; Jagjit Yadav; Suresh Bhargava πŸ“‚ Article πŸ“… 2008 πŸ› Elsevier Science 🌐 French βš– 112 KB

An efficient three-component coupling of aldehydes, amines and alkynes to prepare propargylamines, in nearly quantitative yields using nanocrystalline CuO as a catalyst is described. Structurally divergent aldehydes and amines were converted to the corresponding propargylamines. The reaction does no