Propagation of intercellular calcium waves in PC12 cells overexpressing a carboxy-terminal fragment of amyloid precursor protein
โ Scribed by B.D. Lynn; C.A. Marotta; J.I. Nagy
- Book ID
- 116125098
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 465 KB
- Volume
- 199
- Category
- Article
- ISSN
- 0304-3940
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
In the present study, we investigated effects of estrogen on cell death induced by carboxy-terminal fragment of amyloid precursor protein (CT), a candidate causative substance in the pathogenesis of Alzheimer's disease. 17 beta-Estradiol attenuated CT-induced cell death in PC12 cells, whereas 17 alp
Amyloid plaques, found in characteristically large numbers in specific brain areas of Alzheimer's disease (AD) and Down's Syndrome (DS) patients, are composed of a 4 1 4 3 amino acid peptide, A4, derived from a transmembrane glycoprotein, amyloid precursor protein (APP). In transformed cells APP has