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Promotion of sporulation by caffeine pretreatment insaccharomyces cerevisiae

โœ Scribed by Michio Tsuboi; Naohiko Yanagishima

Publisher
Springer
Year
1975
Tongue
English
Weight
533 KB
Volume
106
Category
Article
ISSN
0302-8933

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โœฆ Synopsis

Cells cultured in the presence of caffeine had high sporulation ability. The sporulation-promotive effect of caffeine was studied, special attention being paid upon changes in nucleic acid metabolism. When transferred to a sporulation medium, the breakdown of RNA, the synthesis of protein, RNA and DNA, commitment to sporulation and the appearance of mature asci took place in caffeine-treated cells significantly earlier than in control cells. Commitment to sporulation occurred before the completion of premeiotic DNA synthesis in both caffeine-treated and control cells.

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