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Promotion of oxidative stress by 3-hydroxyglutaric acid in rat striatum

✍ Scribed by A. Latini; K. Scussiato; G. Leipnitz; C. S. Dutra-Filho; M. Wajner

Publisher
Springer
Year
2005
Tongue
English
Weight
136 KB
Volume
28
Category
Article
ISSN
0141-8955

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## Abstract L‐2‐hydroxyglutaric acid (LGA) is the biochemical hallmark of L‐2‐hydroxyglutaric aciduria (L‐OHGA), an inherited neurometabolic disorder characterized by progressive neurodegeneration with cerebellar and pyramidal signs, mental deterioration, epilepsy, and subcortical leukoencephalopat