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Involvement of oxidative stress in hepatocellular tumor-promoting activity of oxfendazole in rats

✍ Scribed by Yasuaki Dewa; Jihei Nishimura; Masako Muguruma; Meilan Jin; Masaomi Kawai; Yukie Saegusa; Toshiya Okamura; Takashi Umemura; Kunitoshi Mitsumori

Publisher
Springer-Verlag
Year
2008
Tongue
English
Weight
348 KB
Volume
83
Category
Article
ISSN
0340-5761

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✍ Ana-Marija Domijan; Maja Peraica; Ana LuciΔ‡ Vrdoljak; BoΕΎica RadiΔ‡; Vilim Ε½lende πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 196 KB

## Abstract The aim of this study was to find out whether very low doses of nephrotoxic and hepatotoxic mycotoxins ochratoxin A (OTA) and fumonisin B~1~ (FB~1~) induce oxidative stress in rat kidney and liver and whether their effect is synergistic. Rats were treated orally with OTA (5 ng/kg b.w. a