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Promotion of liver regeneration/repair by farnesoid X receptor in both liver and intestine in mice

โœ Scribed by Zhang, Lisheng; Wang, Yan-Dong; Chen, Wei-Dong; Wang, Xichun; Lou, Guiyu; Liu, Nian; Lin, Min; Forman, Barry M.; Huang, Wendong

Book ID
118759141
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
765 KB
Volume
56
Category
Article
ISSN
0270-9139

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Genome-wide tissue-specific farnesoid X
Genome-wide tissue-specific farnesoid X receptor binding in mouse liver and intestine
โœ Ann M. Thomas; Steven N. Hart; Bo Kong; Jianwen Fang; Xiao-bo Zhong; Grace L. Gu ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 648 KB

Farnesoid X receptor (FXR) is a bile acid-activated transcription factor belonging to the nuclear receptor superfamily. FXR is highly expressed in liver and intestine and crosstalk mediated by FXR in these two organs is critical in maintaining bile acid homeostasis. FXR deficiency has been implicate