## Abstract ## Objective Pathologic mineralization is common in osteoarthritic (OA) cartilage and may be mediated by extracellular organelles known as articular cartilage vesicles (ACVs). Paradoxically, ACVs isolated from OA human cartilage mineralize poorly in vitro compared with those isolated f
Promotion of articular cartilage matrix vesicle mineralization by type I collagen
β Scribed by Brian Jubeck; Claudia Gohr; Mark Fahey; Emily Muth; Michele Matthews; Eric Mattson; Carol Hirschmugl; Ann K. Rosenthal
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 215 KB
- Volume
- 58
- Category
- Article
- ISSN
- 0004-3591
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## Objective: To determine the sites of cleavage and denaturation of type ii collagen (cii) by collagenase(s) in healthy and osteoarthritic (oa) human articular cartilage and their relationship to the distribution of matrix metalloproteinase 1 (mmp-1) and mmp-13. ## Methods: Single (per subject)
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