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Promoter polymorphism of the matrix metalloproteinase 3 gene is associated with regurgitation and left ventricular remodelling in mitral valve prolapse patients

โœ Scribed by Oceandy, Delvac; Yusoff, Rahal; Baudoin, Florence M.; Neyses, Ludwig; Ray, Simon G.


Book ID
121833603
Publisher
Oxford University Press
Year
2007
Tongue
English
Weight
260 KB
Volume
9
Category
Article
ISSN
1388-9842

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A functional polymorphism in the matrix
โœ Pornchai O-charoenrat; Piyavadee Leksrisakul; Supatra Sangruchi ๐Ÿ“‚ Article ๐Ÿ“… 2006 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 182 KB ๐Ÿ‘ 2 views

## Abstract Matrix metalloproteinases (MMPs) play an important role in several steps of cancer development. A single guanine insertion polymorphism (2G) in the __MMP1__ promoter sequence at โˆ’1,607 creates an Ets binding site and thus results in enhancing transcriptional activity. This study aimed t