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Promoter methylation of the mutated in colorectal cancer gene is a frequent early event in colorectal cancer

✍ Scribed by Kohonen-Corish, M R J; Sigglekow, N D; Susanto, J; Chapuis, P H; Bokey, E L; Dent, O F; Chan, C; Lin, B P C; Seng, T J; Laird, P W


Book ID
110072211
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
216 KB
Volume
26
Category
Article
ISSN
0950-9232

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## Abstract Bone morphogenic proteins (BMPs) are members of the TGFB growth factor superfamily with well‐described functions in bone formation. Although disrupted BMP signalling in tumor development has more recently been investigated, a role for BMP3 in colorectal cancer (CRC) has remained largely