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Promoter methylation of the hMLH1 gene and protein expression of human mutL homolog 1 and human mutS homolog 2 in resected esophageal squamous cell carcinoma

✍ Scribed by Ching Tzao; Han-Sui Hsu; Guang-Huan Sun; Hsiou-Lei Lai; Yi-Ching Wang; Ho-Jui Tung; Cheng-Ping Yu; Yeung-Leung Cheng; Shih-Chun Lee


Book ID
113760309
Publisher
CTSNet
Year
2005
Tongue
English
Weight
340 KB
Volume
130
Category
Article
ISSN
1097-685X

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## Abstract Esophageal squamous cell carcinoma (ESCC) is the sixth most frequent cause of cancer death in the world, and cigarette smoke is a key factor in esophageal carcinogenesis. To identify molecular changes during cigarette smoke‐induced ESCC, we examined the methylation status of 13 gene pro