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The expression and roles of Id1 and Id2 in the aggressive phenotype of human oral squamous cell carcinoma cells

✍ Scribed by Murase, Ryuichi; Sumida, Tomoki; Liu, Shao hua; Yoshimura, Tomohide; Ishikawa, Akiko; Wei, Feng Cai; Tano, Tomoyuki; Hamakawa, Hiroyuki

Book ID
123348891
Publisher
Elsevier
Year
2013
Tongue
English
Weight
504 KB
Volume
25
Category
Article
ISSN
2212-5558

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## Abstract Inhibitor of differentiation or DNA binding (Id‐1), a helix‐loop‐helix transcription factor, has recently been shown to inactivate the retinoblastoma (RB)/p16^INK4a^ pathway through down‐regulation of p16^INK4a^ and increasing phosphorylation of RB in certain cell types. Nasopharyngeal