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Promoter hypermethylation-mediated down-regulation ofRUNX3gene in human brain tumors

✍ Scribed by Avci, C. B.; Dodurga, Y.; Susluer, S. Y.; Sıgva, Z. O. D.; Yucebas, M.; Caglar, H. O.; Akalin, T.; Dalbasti, T.; Oktar, N.; Gunduz, C.

Book ID
121631610
Publisher
Springer-Verlag
Year
2013
Tongue
English
Weight
284 KB
Volume
183
Category
Article
ISSN
1863-4362

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## Abstract It has recently been demonstrated that CXCL12 is absent in colonic carcinoma, and hypermethylation of CXCL12 contributes to CXCL12/CXCR4 signaling in carcinoma metastasis. However, the role of CXCL12/CXCR4 axis, especially CXCL12, in the regulation of tumor invasiveness is largely still