Promoter characterization and structure of the gene encoding mouse lysosomal α-d-mannosidase
✍ Scribed by S. Stinchi, An. Orlacchio, E. Costanzi, J.L. Stirling, A.R. Menghini, A. Orlacchio, Tommaso Beccari
- Book ID
- 113034868
- Publisher
- Springer-Verlag
- Year
- 1998
- Tongue
- English
- Weight
- 294 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0938-8990
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We have previously reported on a mouse liver-specific genetic polymorphism associated with altered sialylation of lysosomal alpha-mannosidase. A second electrophoretic polymorphism for liver lysosomal alpha-mannosidase has now been found and characterized. This variation, between SWR/J and SM/JCv in
Organ-specific electrophoretic heterogeneity of lysosomal alpha-mannosidase has been observed within individual strains of inbred mice. Polymorphism between C57BL/6J and CBA/J for liver lysosomal alpha-mannosidase is determined by a single genetic locus on chromosome 5 and appears to be the result o