Prominent Langerhans’ cell migration in the arthropod bite reactions simulating Langerhans’ cell histiocytosis
✍ Scribed by Se Hoon Kim; Dong Hyun Kim; Kwang Gil Lee
- Book ID
- 111242190
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 416 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0303-6987
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📜 SIMILAR VOLUMES
A study of 47 well-documented patients with Langerhans cell histiocytosis (LCH) showed a slight female preponderance, with onset as late as the ninth decade. The skin was the commonest site of presentation, but pulmonary and bone involvement was frequent. Patients with single-site disease did best.
Langerhans' cell histiocytosis (LCH) is characterized by an accumulation and/or proliferation of cells with a Langerhans' cell (LC) phenotype. The aetiology and pathogenesis of LCH are unknown; it is suggested that LCH is caused by an immunological dysregulation. Production of cytokines is a central