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Langerhans cell histiocytosis in the adult

✍ Scribed by Malpas, J. S.; Norton, A. J.

Publisher: John Wiley and Sons
Year: 1996
Tongue: English
Weight: 532 KB
Volume: 27
Category: Article
ISSN: 0098-1532
DOI: 10.1002/(sici)1096-911x(199612)27:6<540::aid-mpo6>3.0.co;2-l

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✦ Synopsis

A study of 47 well-documented patients with Langerhans cell histiocytosis (LCH) showed a slight female preponderance, with onset as late as the ninth decade. The skin was the commonest site of presentation, but pulmonary and bone involvement was frequent. Patients with single-site disease did best. The worst prognosis was seen in the elderly or those with organ dysfunction. A high incidence of associated malignant disease was seen, which could precede, be coincidental with, or occur after a diagnosis of LCH.

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