Prolonged inhibition of hepatitis B virus replication with vidarabine monophosphate in chronic active type B hepatitis
โ Scribed by J. GUARDIA; R. ESTEBAN; M. BUTI; R. JARDI; H. ALLENDE; J. I. ESTEBAN
- Book ID
- 114796495
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 301 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0106-9543
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Hepatitis D virus and hepatitis B virus nucleic acids were detected by Northern and Southern blot hybridization in the sera and livers of 86 chronic carriers of HBsAg and anti-hepatitis D followed up for a mean of 10 yr. We identified three subsets of patients 13 with hepatitis D virus and hepatitis
Two patients with chronic type B hepatitis and intercurrent episodes of acute type A hepatitis are presented. Serological markers of hepatitis B virus replication decreased or became undetectable in both patients during the acute illness, while interferon activity was transiently detected in serum.