✦ LIBER ✦

Acute type A hepatitis during chronic hepatitis B virus infection: Association of depressed hepatitis B virus replication with appearance of endogenous alpha interferon

✍ Scribed by Gary L. Davis; Jay H. Hoofnagle; Jeanne G. Waggoner

Publisher: John Wiley and Sons
Year: 1984
Tongue: English
Weight: 435 KB
Volume: 14
Category: Article
ISSN: 0146-6615
DOI: 10.1002/jmv.1890140208

No coin nor oath required. For personal study only.

✦ Synopsis

Two patients with chronic type B hepatitis and intercurrent episodes of acute type A hepatitis are presented. Serological markers of hepatitis B virus replication decreased or became undetectable in both patients during the acute illness, while interferon activity was transiently detected in serum. The presence of serum leukocyte (alpha) interferon was confirmed by neutralization with specific antisera and tests of pH2 stability. These observations suggest a role for natural leukocyte (alpha) interferon in the modulation and control of hepatitis B virus infection and provide further evidence to support trials of exogenous leukocyte (alpha) interferon in the chronic infection.

📜 SIMILAR VOLUMES

Relevance of inapparent coinfection by h

Relevance of inapparent coinfection by hepatitis B virus in alpha interferon-treated patients with hepatitis C virus chronic hepatitis

✍ Zignego, Anna Linda; Fontana, Rossana; Puliti, Silvia; Barbagli, Susanna; Monti, 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 191 KB 👁 2 views

The aim of the study was to investigate whether an ''inapparent'' coinfection by hepatitis B virus (HBV) in anti-HCV-positive chronic liver disease patients may influence interferon (IFN) response. Fourteen anti-HCV-positive, hepatitis B surface antigen (HBsAg)-negative but serum HBV-DNA-positive pa

Effect of duration of hepatitis B virus

Effect of duration of hepatitis B virus infection on the association between human immunodeficiency virus type-1 and hepatitis B viral replication

✍ Beryl A. Koblin; Patricia E. Taylor; Pablo Rubinstein; Cladd E. Stevens 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 350 KB 👁 2 views

This study examined the effect of duration of hepatitis B virus infection on the association between human immunodeficiency virus type-1 infection and hepatitis B viral replication. Twenty-five chronic HBsAg carriers were studied. Presence of hepatitis B virus DNA and expression of HBeAg were more f

Association of concurrent hepatitis B su

Association of concurrent hepatitis B surface antigen and antibody to hepatitis B surface antigen with hepatocellular carcinoma in chronic hepatitis B virus infection

✍ Ji Sun Jang; Hyoung Su Kim; Ha Jung Kim; Woon Geon Shin; Kyung Ho Kim; Jin Heon 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 152 KB 👁 1 views

## Abstract Antibody to hepatitis B surface antigen (HBsAg) (anti‐HBs) can exist in patients with chronic hepatitis B virus (HBV) infection. To date, little is known about the association of concurrent HBsAg and anti‐HBs (concurrent HBsAg/ anti‐HBs) with hepatocellular carcinoma (HCC). The aim of t

Production of interferon alpha and inter

Production of interferon alpha and interferon gamma by peripheral blood leukocytes from patients with chronic hepatitis B virus infection

✍ Dr. Jochen Abb; Vera Zachoval; Friedrich Deinhardt; Gerd R. Pape; Reinhart Zacho 📂 Article 📅 1985 🏛 John Wiley and Sons 🌐 English ⚖ 324 KB

Peripheral blood leukocytes from patients with chronic hepatitis B virus (HBV) infection were studied for their capacity to produce interferon (IFN) alpha or IFN gamma. Yields of IFN alpha in leukocyte cultures stimulated with influenza A virus or human leukemic cells were significantly lower than t

Association of estrogen receptor α polym

Association of estrogen receptor α polymorphisms with susceptibility to chronic hepatitis B virus infection

✍ Guohong Deng; Gangqiao Zhou; Yun Zhai; Shuqing Li; Xuhong Li; Ya Li; Ruifang Zha 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 173 KB

Several studies have demonstrated that estrogen receptor alpha (ESR1) participates in the pathogenesis of persistent hepatitis B virus (HBV) infection. To examine whether polymorphisms at the ESR1 gene locus are associated with persistent HBV infection, we resequenced ESR1 genomic region for single

δ-Infection and suppression of hepatitis

δ-Infection and suppression of hepatitis B virus replication in chronic HBsAg carriers

✍ Kim Krogsgaard; Peter Kryger; Jan Aldershvile; Poul Andersson; Thorkild I. A. Sø 📂 Article 📅 1987 🏛 John Wiley and Sons 🌐 English ⚖ 436 KB

The presence of hepatitis B virus DNA and anti-b was examined in a longitudinal study of 24 patients known to be &infected during the course from acute to chronic hepatitis B virus infection. Fifteen patients (63%) were hepatitis B virus DNA positive in the first serum sample. Eleven of 14 patients,