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Proline-Catalyzed Mannich Reaction of Aldehydes with N-Boc-Imines.

✍ Scribed by Jung Woon Yang; Michael Stadler; Benjamin List

Book ID
102004644
Publisher
John Wiley and Sons
Year
2007
Weight
28 KB
Volume
38
Category
Article
ISSN
0931-7597

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✦ Synopsis

Abstract

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The Proline-Catalyzed Double Mannich Rea
The Proline-Catalyzed Double Mannich Reaction of Acetaldehyde with N-Boc Imines
✍ Carley Chandler; Patrizia Galzerano; Anna Michrowska; Benjamin List 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 318 KB 👁 1 views

## Abstract **Doppelkreuz**: Prolin katalysiert doppelte Mannich‐Reaktionen von Acetaldehyd mit __N__‐Boc‐Iminen, die ausgezeichnete Ausbeuten ergeben (bis 99 %; Boc=__tert__‐Butoxycarbonyl) und mit annähernd vollständigen Diastereo‐ und Enantioselektivitäten verlaufen. Je nach Wahl des Katalysator