Proline-Catalyzed Direct Asymmetric Aldol Reactions
β Scribed by List, Benjamin; Lerner, Richard A.; Barbas, Carlos F.
- Book ID
- 115480200
- Publisher
- American Chemical Society
- Year
- 2000
- Tongue
- English
- Weight
- 120 KB
- Volume
- 122
- Category
- Article
- ISSN
- 0002-7863
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Direct aldol reactions of several aromatic aldehydes with ketones using L-proline-2,4,6-trinitroanilide catalyst 2d were conducted. Under optimized conditions, high enantioselectivity (99% ee), regioselectivity (up to 95:5), and diastereoselectivity (up to 98:2) were achieved.
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.