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Proliferation of human malignant astrocytomas is dependent on Ras activation

✍ Scribed by Guha, Abhijit; Feldkamp, Matthias M; Lau, Nelson; Boss, Gerry; Pawson, Anthony


Book ID
110061030
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
297 KB
Volume
15
Category
Article
ISSN
0950-9232

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✍ Emilie Sick; Abdelaziz Boukhari; ThΓ©rΓ¨se Deramaudt; Philippe RondΓ©; Bernard Buch πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 963 KB

CD47 is a membrane receptor that plays pivotal roles in many pathophysiological processes, including infection, inflammation, cell spreading, proliferation, and apoptosis. We show that activation of CD47 increases proliferation of human U87 and U373 astrocytoma cells but not normal astrocytes. CD47