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Activation of Amyloid Precursor Protein Processing by Growth Factors is Dependent on Ras GTPase Activity

✍ Scribed by Loredana Amigoni; Michela Ceriani; Fiorella Belotti; Giuseppina Minopoli; Enzo Martegani

Publisher
Springer
Year
2010
Tongue
English
Weight
293 KB
Volume
36
Category
Article
ISSN
0364-3190

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The role of diacylglycerol (DAG) in hormonal induction of S phase was investigated in primary cultures of rat hepatocytes. In this model, several agonists that bind to G protein-coupled receptors act as comitogens when added to the cells soon after plating (i.e., in Go/early Gl phase), while the cel