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Proliferation-based T-cell selection for immunotherapy and graft-versus-host-disease prophylaxis in the context of bone marrow transplantation

โœ Scribed by Pachnio, A; Dietrich, S; Klapper, W; Humpe, A; Schwake, M; Sedlacek, R; Gramatzki, M; Beck, C


Book ID
110015039
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
388 KB
Volume
38
Category
Article
ISSN
0007-1188

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Selective depletion of marrow-T cytotoxi
โœ D. Maraninchi; C. Mawas; D. Guyotat; J. Reiffers; J. P. Vernant; N. Gratecos; J. ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› Springer ๐ŸŒ English โš– 418 KB

In vitro depletion of mature pan-T lymphocytes has been widely and successfully used to prevent acute graft-versus-host disease (GVHD) after allogeneic bone-marrow transplantation (BMT). However, this procedure has been associated with a high incidence of graft failure and leukemic relapse. In this