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Selective depletion of marrow-T cytotoxic lymphocytes (CD8) in the prevention of graft-versus-host disease after allogeneic bone-marrow transplantation

✍ Scribed by D. Maraninchi; C. Mawas; D. Guyotat; J. Reiffers; J.P. Vemant; N. Gratecos; J. Hirn; G. Novakovitch


Book ID
115133918
Publisher
Springer
Year
1988
Tongue
English
Weight
331 KB
Volume
1
Category
Article
ISSN
0934-0874

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Selective depletion of marrow-T cytotoxi
✍ D. Maraninchi; C. Mawas; D. Guyotat; J. Reiffers; J. P. Vernant; N. Gratecos; J. πŸ“‚ Article πŸ“… 1988 πŸ› Springer 🌐 English βš– 418 KB

In vitro depletion of mature pan-T lymphocytes has been widely and successfully used to prevent acute graft-versus-host disease (GVHD) after allogeneic bone-marrow transplantation (BMT). However, this procedure has been associated with a high incidence of graft failure and leukemic relapse. In this