Senescence of cultured human diploid fib
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Radhey S. Gupta
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Article
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1980
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John Wiley and Sons
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English
β 691 KB
## Abstract Two predictions of the error/mutation hypothesis of cellular sensecence (Orgel, '73) namely, (a) exponential accumulation of somatic mutations during the replicative lifespan and (b) shortening of culture lifespan upon treatment with mutagens have been examined experimentally in a strai